Those taking the highest doses also saw the greatest reduction in the percentage of inflammatory T cells, which are believed to be responsible for most MS symptoms.
In a test of 40 MS sufferers, some were given 10,400 IUs of the vitamin every day for six months, and their symptoms were compared to those given 800 IUs. The recommended daily intake for a healthy person is 600 IUs.
Researchers from Johns Hopkins Multiple Sclerosis Centre found that those given the higher dose were also better able to regulate their hyperactive immune response.
Both doses were well tolerated, and any side effects were minimal.
It’s already known that people with low levels of vitamin D3 are more likely to develop MS, and they are also more likely to suffer greater disability and more severe symptoms once they have the disease.
(Source: Neurology, 2015; doi: 10.1212/WNL.00000000000002316)
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