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Ginseng could be better than drugs to treat osteoporosis

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Female ginseng is a popular remedy in Traditional Chinese Medicine (TCM) for osteoporosis—and it really does work.

Scientists have identified two compounds in female ginseng (Angelica sinensis) that can combat osteoporosis, a bone-weakening condition that becomes more common as we get older.  

Researchers from the American Chemical Society isolated the two compounds and tested them on cells known as osteoclasts, which create bone loss.  They blocked the cells and stopped them forming molecular pathways that would allow them to spread through bone tissue.

Female ginseng could be an effective alternative to anti-osteoporosis drugs such as Fosamax, which resulted in $27m of settlements after its manufacturer, Merck, was accused of producing a drug that caused femur fractures and weakening of the jawbone.  Other anti-osteoporosis drugs include Aledronic acid, which can cause ulcers on the food pipe (esophagus).

References
ACS Central Science, 2024; doi: 10.1021/acscentsci.2c01414
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