Close X
Get more out of WDDTY.com
by joining the site for free
Free 17-point plan to great health
Twice weekly e-news bulletins
Access to our News, Forums and Blogs
Sign up for free and claim your
17-point plan to great health
Free 17-point plan to great health

Twice weekly e-news bulletins

Access to our News, Forums and Blogs
OR

If you want to read our in-depth research articles or
have our amazing magazine delivered to your home
each month, then you have to pay.


Click here if you're interested
Helping you make better health choices

What Doctors Don't Tell You

In shops now or delivered to your home from only £3.50 an issue!

Subscribe!
May 2019 (Vol. 4 Issue 3)

The key molecule that makes exercise effective
About the author: 
Bryan Hubbard

The key molecule that makes exercise effective image

Exercise can help you lose body fat, and especially around the abdomen—but only if one of your molecules is working efficiently.

Interleukin-6, a signalling molecule, plays a key role in losing fat after exercise, researchers have discovered, overturning the prevailing belief that it's all down to the fight-or-flight hormone, epinephrine.

Researchers from the University of Copenhagen noticed that obese people who were taking the rheumatoid arthritis drug tocilizumab weren't losing abdominal fat. The drug increases cholesterol levels—and also blocks interleukin-6 activity.

They tested the theory on a group of 53 obese participants who took part in a 12-week exercise programme, which included regular sessions on a static exercise bike. Half were given a saline placebo drip, and the rest were instead drip-fed the drug.

Those on the saline drip lost around 8 per cent of visceral fat—which accumulates around the heart and liver—but there was no fat loss among those given tocilizumab. They also had higher levels of cholesterol as a result of taking the drug.

People who are obese or suffer from type 2 diabetes or heart disease tend to either have low levels of interleukin-6, the researchers say, or whose interleukin isn't signalling healthily.


References

(Source: Cell Metabolism, 2018; doi: 10.1016/j.cmet.2018.12.007)

You may also be interested in...

Latest Tweet

About

Since 1989, WDDTY has provided thousands of resources on how to beat asthma, arthritis, depression and many other chronic conditions..

Start by looking in our fully searchable database, active and friendly community forums and the latest health news.

Positive SSL Wildcard

Facebook Twitter

© 2010 - 2019 WDDTY Publishing Ltd.
All Rights Reserved