The American drug regulator, the Food and Drug Administration, is so concerned that it is considering restricting the drug's availability, an action that has already been taken in Ireland. There, it is illegal to buy more than 24 tablets, or 500 mg, in a single transaction. Despite this, it was responsible for nearly a third of all the 7,933 drug overdoses recorded in Ireland in 2004.
The drug can become dangerous at even relatively low dosages, and can cause serious - and sometimes fatal - liver damage.
(Source: The Lancet, 2007; 369: 1346).
E-news broadcast 3 May 2007 No.356