Astonishingly for such a prevalent condition, not one of the 25 standard antidepressants has been approved for use for the disorder, even though doctors regularly prescribe them to patients.
And, according to a new Harvard study, they're wasting their time. A group of 366 bipolar sufferers were given either a mood stabilizer and antidepressant, or a mood stabilizer and a placebo - but the drug wasn't any more effective than the placebo. Levels and frequency of mania were similar in both groups.
(Source: New England Journal of Medicine, 2007; 356: 1711-22).
E-news broadcast 26 April 2007 No.354 [Subscribe]