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Organ transplant patients risk drug resistant virus
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Analysis of cytomegalovirus (CMV) disease among 240 liver, kidney and pancreas recipients has shown that the incidence of CMV is higher than previously thought

Analysis of cytomegalovirus (CMV) disease among 240 liver, kidney and pancreas recipients has shown that the incidence of CMV is higher than previously thought.

A total of 25 patients had CMV disease within a year of transplantation. All had been taking oral ganciclovir to prevent the disease.

Five of these patients developed a ganciclovir resistant form of CMV infection with "serious clinical consequences". Each had been taking particularly large doses of ganciclovir to suppress a likely immune reaction to the organ received (Lancet, 2000; 356: 645-9).


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