Close X
Get more out of WDDTY.com
by joining the site for free
Free 17-point plan to great health
Twice weekly e-news bulletins
Access to our News, Forums and Blogs
Sign up for free and claim your
17-point plan to great health
Free 17-point plan to great health

Twice weekly e-news bulletins

Access to our News, Forums and Blogs
OR

If you want to read our in-depth research articles or
have our amazing magazine delivered to your home
each month, then you have to pay.


Click here if you're interested
Helping you make better health choices

In shops now or delivered to your home from only £3.50 an issue!

Subscribe!

Down's syndrome: it's not the age of the mother that counts after all
About the author: 

Down's syndrome is something that every expectant mother worries about, especially if she is over 30 years old

Down's syndrome is something that every expectant mother worries about, especially if she is over 30 years old.

But researchers from Tel Aviv University have discovered that the link is much more to do with the woman's inability to metabolise folate and methyl. This is a characteristic of neural-tube defects (NTD), which includes spina bifida. It is this lack, rather than age, that is the more significant marker.

Although a dose of just 0.4 mg of folic acid every day was believed to be enough to protect against NTD, the researchers say a dose of around 5 mg is needed. The effect is amplified if the woman also takes cobalamin.

Other researchers have suggested that women need only eat food that is fortified with folic acid, but the Tel Aviv research team argues that supplementation works far better as a preventative. This last recommendation is significant, and goes against the general view that fortified food, and especially flour, is sufficient to raise the nutritional status of most women.

Interestingly, the Birth Defects Foundation in the UK supports supplementation, and urged women to continue taking folic acid in the wake of the recent Food Standards Agency report that seemed to suggest all vitamins and supplements were, at best, lethal.

(Source: The Lancet, 2003; 361: 1331-5).


You may also be interested in...

Latest Tweet

About

Since 1989, WDDTY has provided thousands of resources on how to beat asthma, arthritis, depression and many other chronic conditions.

Start by looking in our fully searchable database, active and friendly community forums and the latest health news.

Positive SSL Wildcard

Facebook Twitter

Most Popular Health Website of the Year 2014

© 2010 - 2017 WDDTY Publishing Ltd.
All Rights Reserved