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Angiotensin-ii blockers further side-effects

MagazineJanuary 2006 (Vol. 16 Issue 10)Angiotensin-ii blockers further side-effects

- liver failure- allergic reactions- a decrease in white blood cells- headache- drowsiness- diarrhoea- abnormal taste sensation (salty or metallic taste)- skin rash- cough (though less frequently than with ACE inhibitors)

- liver failure
- allergic reactions
- a decrease in white blood cells
- headache
- drowsiness
- diarrhoea
- abnormal taste sensation (salty or metallic taste)
- skin rash
- cough (though less frequently than with ACE inhibitors).
ARB- and ACE inhibitor-induced head-and-neck angioedema - characterised by deep, mucosal swelling, and sometimes difficulty swallowing and breathing - has also been reported (Arch Otolaryngol Head Neck Surg, 2004; 130: 1416-9).

Candesartan, eprosartan and telmisartan have all been shown to enter breast milk. In fact, most drugs in this class are contraindicated during pregnancy, especially in the second and third trimesters, as they can cause birth defects.

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