Helping you make better health choices

In shops now or delivered to your home from only £3.50 an issue!


Latest analysis reaffirms the danger of hrt

MagazineNovember 2002 (Vol. 13 Issue 8)Latest analysis reaffirms the danger of hrt

A new British review has concluded that a woman taking HRT is more likely to contract a life-threatening disease than be protected against one

A new British review has concluded that a woman taking HRT is more likely to contract a life-threatening disease than be protected against one.

The analysis of four major studies, involving 20,000 postmenopausal women taking HRT for five years, found that such women in their 50s had a higher risk of breast cancer, while those in their 60s had greater chances of stroke or pulmonary embolism (blood clots in the lung).

The researchers estimated that, over five years, there would be six extra cases of breast cancer, stroke or pulmonary embolism for every 1000 healthy women aged 50-59 taking HRT. The number doubles to 12 per 1000 for users aged 60-69.

Reductions in the number of expected cases of bowel cancer or hip fracture were low at 1.7 and 5.5, respectively, per 1000 HRT users in the two age groups (Lancet, 2002; 360: 942-4).

These results support the Women's Health Initiative (WHI) study of healthy women taking HRT, halted earlier this year because of health risks with HRT, and show no changes in the risks of endometrial cancer or coronary heart disease.

In another study, postmenopausal HRT raised levels of C-reactive protein (CRP), one of several inflammatory markers of increased cardiovascular risk (JAMA, 2002; 288: 980-7). Using data from the WHI, it was noted that women with high levels of CRP were more likely to suffer a heart attack or fatal heart failure within three years of starting HRT.

Among women with high CRP levels, HRT use increased CRP levels by 55 per cent vs women with normal CRP levels. These latter women had CRP levels that were raised 70 per cent vs healthy women not taking HRT.

These new findings mean that doctors can no longer safely recommend HRT for every menopausal ill (JAMA, 2002; 288: 882-4).

A ruined life, thanks to mental services

Selenium disappearing from depleted soils

You may also be interested in...

Sign up for free today

Sign up now to get your FREE 17-point Plan to Great Health

Free membership gives you access to our latest news reports, use of our community area, forums, blogs, readers' health tips and our twice-weekly
e-news letter.

WDDTY Recommends

Latest Tweet


Since 1989, WDDTY has provided thousands of resources on how to beat asthma, arthritis, cancer, depression and many other chronic conditions.

Start by looking in our fully searchable database, active and friendly community forums and the latest health news.

Positive SSL Wildcard

Facebook Twitter

Most Popular Health Website of the Year 2014

© 2010 - 2016 WDDTY Publishing Ltd.
All Rights Reserved