Helping you make better health choices

In shops now or delivered to your home from only £3.50 an issue!

Subscribe!

Eletriptan

MagazineJune 2000 (Vol. 11 Issue 3)Eletriptan

Eletriptan is one of the newer breed of triptans for treating migraine, following in the wake of the more famous sumatriptan

Eletriptan is one of the newer breed of triptans for treating migraine, following in the wake of the more famous sumatriptan. It's cheaper, and is more effective than oral sumatriptan and a recent major trial reports that it also comes with similar adverse reactions.

The triptan family tries to control migraine attacks by changing serotonin (5-HT) levels, which also affect depression and psychosis.

However, their effectiveness can be hit or miss as they are poorly absorbed by the gut. As a result, only around two thirds of patients are ever helped by the triptans. Even the later injected triptans have a relatively high failure rate, and are also much more expensive. The injected variety of sumatriptan also comes with more adverse reactions.

The triptans are no go drugs for people suffering from a heart condition as they can cause chest pains in up to 8 per cent of patients.

The later triptans, including eletriptan, naratriptan and rizatriptan, were supposed to come without the reactions associated with sumatriptan. But a recent study on eletriptan suggests it comes with all the usual side effects (Neurology 2000; 54: 156-63).

Flushing, palpitations, nasal discomfort, eye irritation, visual disturbance and agitation were all symptoms reported way above the placebo group.

In a critique of triptans by Nicholas Bateman of the Scottish Poisons Information Bureau, there seems little to choose between them (Lancet 2000; 355: 860-1). Naratriptan seems to have fewer adverse reactions, but acts more slowly.

A better agent for treating migraine is still needed, he believes. Especially as regular use of any of the triptans can produce an increase in migraine frequency and headache (Lancet 1999; 353: 378).

Which, as Hamlet might have said, is a real bummer.


Diet and exercise beat my crohn's disease

If you have non hodgkin's lymphoma, or wish to prevent it from developing. . .

You may also be interested in...

Sign up for free today

Sign up now to get your FREE 17-point Plan to Great Health

Free membership gives you access to our latest news reports, use of our community area, forums, blogs, readers' health tips and our twice-weekly
e-news letter.

WDDTY Recommends

Latest Tweet

About

Since 1989, WDDTY has provided thousands of resources on how to beat asthma, arthritis, cancer, depression and many other chronic conditions.

Start by looking in our fully searchable database, active and friendly community forums and the latest health news.

Positive SSL Wildcard

Facebook Twitter

Most Popular Health Website of the Year 2014

© 2010 - 2016 WDDTY Publishing Ltd.
All Rights Reserved