Helping you make better health choices

In shops now or delivered to your home from only £3.50 an issue!

Subscribe!

Sertraline

MagazineJune 1997 (Vol. 8 Issue 3)Sertraline

"Reason to be cheerful" chirrups the advertisement for sertraline, a heavyweight antidepressant for people who have suffered a major bout of depression, and who may have attempted suicide

"Reason to be cheerful" chirrups the advertisement for sertraline, a heavyweight antidepressant for people who have suffered a major bout of depression, and who may have attempted suicide. Manufactured by Pfizer, it's marketed in the UK as Lustral an

As a selective serotonin reuptake inhibitor (SSRI), setraline can be fatal if taken with a monoamine oxidase inhibitor (MAOI). Early warning signs of a likely drug interaction include confusion, irritability and extreme agitation which leads to delirium and coma, and possibly death. These reactions have also been noticed in people who have recently come off an SSRI and started a MAOI.

You are advised to wait at least 14 days between taking either of the drugs.

Similarly, the drug should be prescribed to people with liver disease only with caution, Pfizer advises. Overall, it's designed for short term use of up to 16 weeks at a daily dosage of 50 mg.

Even without the help of a MAOI, sertraline can pack a punch all on its own. The most common reactions include gastrointestinal complaints, including nausea, diarrhea, tremors, dizziness, insomnia, sleepiness, sweating, dry mouth and male sexual dysfunction.

In premarketing trials, 15 per cent of the 2700 patients the drug was tested on had to come off sertraline because of an adverse reaction. Central nervous system disorders come a close second to the gastrointestinal ones in terms of frequency, and include headaches, dizziness and tremors.

Then, of course, there are the paradoxical effects of drugs in other words, they cause the very symptoms they are supposed to be treating. Setraline can cause abnormal dreams, aggression, amnesia, delusion, depersonalization, hallucinations, and, yes, depression, aggravated depression and suicidal tendencies.

Reason to be cheerful indeed.


Where are the real risk areas?

You may also be interested in...

Sign up for free today

Sign up now to get your FREE 17-point Plan to Great Health

Free membership gives you access to our latest news reports, use of our community area, forums, blogs, readers' health tips and our twice-weekly
e-news letter.

WDDTY Recommends

Latest Tweet

About

Since 1989, WDDTY has provided thousands of resources on how to beat asthma, arthritis, cancer, depression and many other chronic conditions.

Start by looking in our fully searchable database, active and friendly community forums and the latest health news.

Positive SSL Wildcard

Facebook Twitter

Most Popular Health Website of the Year 2014

© 2010 - 2016 WDDTY Publishing Ltd.
All Rights Reserved