Close X
Get more out of WDDTY.com
by joining the site for free
Free 17-point plan to great health
Twice weekly e-news bulletins
Access to our News, Forums and Blogs
Sign up for free and claim your
17-point plan to great health
Free 17-point plan to great health

Twice weekly e-news bulletins

Access to our News, Forums and Blogs
OR

If you want to read our in-depth research articles or
have our amazing magazine delivered to your home
each month, then you have to pay.


Click here if you're interested
Helping you make better health choices

In shops now or delivered to your home from only £3.50 an issue!

Subscribe!

Vioxx

About the author: 

It's been discovered that the discredited painkiller Vioxx had been approved for use by children just days before the manufacturer removed it from the market

It's been discovered that the discredited painkiller Vioxx had been approved for use by children just days before the manufacturer removed it from the market.
The drug, one of the new generation of painkillers known as COX-2 inhibitors, almost doubles the risk of heart attack and stroke in patients who had taken the drug for 18 months. America's drug watchdog, the Food and Drug Administration, reckons that Vioxx may have caused more than 27,000 heart attacks in the four years it has been on the market, of which 7,000 have been fatal.
So it's especially surprising that it was the FDA that approved the drug for pediatric use, a decision taken after studying a three-month trial carried out by the manufacturer on a group of children. An FDA spokesman told a newspaper that the decision was the correct one based on the information available at the time. Paradoxically, he added that it was also the correct decision of the manufacturer to withdraw the drug.
It's an odd statement to make bearing in mind the enormous amount of information that was already pointing to the drug's dangers. It was even taken up by one of the FDA's own officials, who found even more evidence of a link to cardiovascular disorders. The agency chose to ignore his findings as they did not meet the 'gold standard' of research, presumably meaning it was not derived from the double-blind placebo study beloved of medical researchers.
Even so, there were still plenty of 'gold standard' studies that might have given the FDA pause. Back in February, 2000 What Doctors Don't Tell You was telling its readers that common adverse reactions included abdominal pains, dizziness, fluid retention, and hypertension, and three years later was able to confirm that Vioxx patients were twice as likely to suffer a cardiovascular problem than those taking a NSAID (non steroidal, anti-inflammatory drug), one of the older generation of painkillers.
Last week the European Medicines Evaluation Agency finally entered the fray, and ordered a safety review of the COX-2 family.
The COX-2 saga raises a number of questions about drug safety and regulation. How did this drug get approval in the first place? And why didn't the drug regulators act sooner when they knew full well that there were serious problems with the drugs? And how could the FDA approve the drug for use among children with the information at its disposal?
Of course Vioxx is not an isolated case. There are many drugs still on the market that should be withdrawn, and it's something our watchdogs - ostensibly there for our protection - know all about.


Pregnant women:

Osteoporosis and natural remedies:

You may also be interested in...

Latest Tweet

About

Since 1989, WDDTY has provided thousands of resources on how to beat asthma, arthritis, depression and many other chronic conditions.

Start by looking in our fully searchable database, active and friendly community forums and the latest health news.

Positive SSL Wildcard

Facebook Twitter

Most Popular Health Website of the Year 2014

© 2010 - 2017 WDDTY Publishing Ltd.
All Rights Reserved