There have been some amazing claims made for MSM (MethylSulphonylMethane), and especially as an anti-arthritic. But what do you all think? If you do try it, says one reader, it should be used with aloe vera, as this can act as a carrier for the MSM. It should be applied topically to the troubled joints. Another reader tried it, and she suffered 'truly awful' indigestion and diarrhoea, which were described as possible minor side effects. They seemed far from minor at the time, our reader says. Instead she now uses a vegetarian version of glucosamine (she is allergic to shellfish, which most versions contain) made by Healthspan, along with boswellia as an anti-inflammatory. After three months the combination is starting to have a positive effect.