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Suppress to impress

CommunityBlogsBryan Hubbard2008JanuarySuppress to impress

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Bryan Hubbard is Publisher and co-editor of WDDTY. He is a former Financial Times journalist. He is a Philosophy graduate of London University. Bryan is also the author of several books, including The Untrue Story of You and Secrets of the Drugs Industry.

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Suppress to impress

January 25th 2008, 15:06
7,569 views

What shall we do with the drug companies? The year is only a few weeks old but already they've been caught out on two occasions suppressing vital data that revealed their drugs weren't working anywhere near as well as they have claimed.

In the first case - involving the cholesterol-lowerting drug Zetia (ezetimibe) - the truth about its inneffectiveness was revealed only when a Congressional hearing in the USA forced the manufacturer to release the data from its Enhance trial.

In the second, independent researchers discovered that selective reporting of data from trials into a range of antidepressants had made them seem at least 30 per cent more effective than in fact they were.

America's drug regulator, the Food and Drug Administration (FDA), has one answer. From next September, every drug trial must be registered with the agency, and ongoing reearch and findings must be revealed other than during the first, preliminary stages.

The worry is that the ruling has no teeth. Drug companies that fail to comply can be fined a whopping $10,000 (UKlb5,100), which will certainly make them think twice before suppressing data on drugs that generate billions of dollars of sales every year.

Still, it's an attempt of sorts, we suppose, and we don't expect the UK's drug regulators - who pride themselves on being the fastest in the world - to come up with anything similar any time soon.

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