Hrt and stroke:more bad news

Findings from the US Nurses' Health Study showed that women who use oestrogen replacement therapy at just 0.625 mg/day have 1.35 times the risk of stroke of non users. Those taking 1.25 mg/day or more have more than one and a half times the risk of n

While the study did not find any increased risk of heart disease, the researchers warn that it is still too early to recommend prescribing HRT to prevent heart disease, and that larger trials are needed to confirm the effectiveness and safety of HRT in this area (Ann Intern Med, 2000; 133: 933-41, 999-1001).

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