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Drugs drug alerts - Asthma drugs: they are safe, really, aren’t they?

In 1996 Advair (salmeterol plus fluticasone propionate) was tested for its safety against a placebo, and researchers found a ''small, but significant'' increase in the death rate among patients.

The American drugs regulator, the Food and Drug Administration, acted in the way it knows best, and ordered a ‘label revision’. This is a harsh penalty, requiring a minute change to the small print.

The FDA’s drug advisory committee finally met up the other week to decide if the drugs should be allowed to stay on the market. To a man, they decided that the drugs were safe enough to continue to be prescribed (Lancet, 2005; 366: 266).

Asthma drugs: - They are safe, really, aren't they? - When it comes to drug safety, how safe is safe?

Serevent - The story so far: Serevent (salmeterol xinafoate) is a beta-agonist inhaler for asthmatics. Deaths were so quickly associated with the drug following...

Asthma sufferers: heart problems - Asthma sufferers who use beta-agonist inhalers run twice the risk of dying from a heart condition than those using other treatments. ...

Asthma drugs: - Bronchodilators double death risk in first 12 months - Asthma drugs have had a chequered past, going back to the early 1960s when the non-selective beta-agonist isoprenaline was withdrawn. Since then worr...

Advair - Business as usual - Clever people, those City and Wall St folks. The share price of drug giant GlaxoSmithKline (GSK) fell 4 per cent in just one day’s trading this week a...

New drugs - New profits for old product - Most new drugs are simply old drugs with a bit of window dressing to justify double the price tag. Yet, the dangers multiply from these novel twists a...

Serevent - The wheels of power in medicine lurch slowly, and there are occasions when it’s as well to be considered and reflective. These virtues become vices, h...

Asthma drugs cause deaths - Certain asthma drugs, particularly those used in inhalants, could be contributing to the increase in the number of deaths from asthma. ...

The British Institute for the Identification & Treatment of Allergic Disorders

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