Click here to read about some of the people we've helped.  We're here to help you, too. Get four essential health reports by joining our e-news community.

Four FREE health reports for you

Register now for our vital and insightful health updates, and get four free health reports to help you live more healthily.

First Name:Email:


Epilepsy drugs can spark serious skin disorders

A range of epilepsy drugs can cause serious skin disorders, such as Stevens-Johnson syndrome and toxic epidermal necrolysis.

Researchers examined 352 sufferers of either of the two skin problems and found that 73, or 21 per cent, were taking an antiepileptic drug. Of these, 36 were prescribed phenobarbital, 14 were taking phenytoin, 21 were on carbamazepine, 13 on valproic acid and three on lamotrigine. Those who reacted to valproic acid tended to be taking other drugs as well.

The research team, from Mannheim University in Germany, said the risk usually fell within the first eight weeks of drug therapy (Lancet, 1999; 353: 2190-4).



WDDTY Blog Speak

Seizure medication linked to skin disease seizure medication linked t - Novartis has issued new warnings for its antiepilepsy drug Trileptal (oxcarbazepine) that highlight the drug’s serious skin-related side-effects such...

Phenobarbital: - If it's good enough for our dogs - Phenobarbital, the world's oldest epilepsy drug, has fallen out of favour in the last decade or so. In the UK doctors have been forbidden to prescrib...

Lamotrigine - Our Drug of the Month was prompted by one of our readers. After reading our epilepsy cover story (WDDTY Vol 6 no 8), she wondered whether she could sw...

Septrin - the risks - Q:I have heard of a horrendous case of Septrin causing the most severe side effects in a penicillin allergic subject. I understand that this drug is...

The epilepsy newcomer - Lamotrigine (marketed as Lamictal) is one of the new-generation antiepileptic drugs (AEDs) brought in as an alternative to the traditionally prescribe...

More harm from epilepsy medication - New studies suggest that many of the available antiepileptic drugs, especially the older ones, can have other negative effects besides worsening seizu...

Drugs for epilepsy - Q:I first had an epileptic seizure 32 years ago, and for the following 10 years had about two grandmal seizures a year. Following the first episode...

Herbs for skin problems - Eczema, now on the increase among young children, is a worry to mothers, not least because the 'cure' which usually contains steroids is often far wor...