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Candida drug questions

Several possible risks have emerged with fluconazole, marketed here by Pfizer as Diflucan, the once a day oral or injectable court of last resort anti candida drug.

A 22 year old woman with no previous allergies was given fluconazole orally to treat vaginal candida.

Within a few minutes she developed a severe anaphylactic (or hyper sensitive) reaction, including several oedema and hypotension, to the point where her pulse was barely detectable.

The writers, two doctors from the University of Basle in Switzerland, believe the woman could have been sensitized to fluconazole after taking two imidazole derivatives (ketoconazole and metronidazole) earlier for the same problem.

In the same issue of The Lancet, a correspondent complained about the failure of the drug to treat candida in a burns patient, who went on to receive successful treatment with amphotericin B.

This correspondent was the latest of a number to complain about the drug's failure to work in certain conditions.



WDDTY Blog Speak

Diflucan (fluconazole) - Diflucan (fluconazole) was sold to doctors as the "elegant" way to deal with vaginal thrush (yeast infections). A single 150 mg pill would rid their...

Candida - New theories, new cures - Twenty years after Orion Truss discovered candida, many practitioners now believe the story is more complicated and that natural alternatives are bett...

Metronidazole - Neurological symptoms with FlagylA number of studies have shown peripheral neuropathy - nerve damage outside of the brain and spinal cord - to be amon...

Metronidazole - This drug (Flagyl) is among the most widely prescribed antibiotics for the treatment of bacterial vaginosis (BV) in pregnant women - this despite the...

Drug immune candida detected - A new form of candida is developing in North America which is resistant to anti fungal agents. ...

Candida: the missing links - A noted allergy specialist questions many of the most common assumptions about candida overgrowth. ... ...

Hypotension, or low blood pressure - Q I have read a lot about hypertension, but not much about hypotension, which my friend suffers from. Having low blood pressure makes her very tired a...

Antifungals - Other effects - It’s wise to remember that this type of drug, an ‘azole’, is similar to some of the systemic antifungal polyenes like amphotericin B. All of these typ...