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Different drugs, different risks

Each type of antiepileptic drug brings with it the risk of different types of seizures.

Antiepileptic drug Type of seizure

Phenytoin A variety of different types (has the highest risk of inducing a seizure)
Phenobarbital Negative myoclonus, tonic and absence
Benzodiazepines Tonic-clonic
Carbamazepine Tonic, atonic, absence, myoclonic
Oxcarbazepine Absence and myoclonic
Sodium valproate Myoclonic and status epilepticus
Ethosuximide Generalised non-convulsive and atonic
Lamotrigine Myoclonic
Gabapentin Absence and myoclonic
Vigabatrin Myoclonic



WDDTY Blog Speak

Lamotrigine - Our Drug of the Month was prompted by one of our readers. After reading our epilepsy cover story (WDDTY Vol 6 no 8), she wondered whether she could sw...

Phenobarbital: - If it's good enough for our dogs - Phenobarbital, the world's oldest epilepsy drug, has fallen out of favour in the last decade or so. In the UK doctors have been forbidden to prescrib...

Epilepsy: It’s wrongly diagnosed in one out of four cases - Epilepsy drugs take no prisoners. Their number reads more like a ‘most wanted’ list, and includes phenobarbitone, phenytoin, primidone, carbamazepine,...

The epilepsy newcomer - Lamotrigine (marketed as Lamictal) is one of the new-generation antiepileptic drugs (AEDs) brought in as an alternative to the traditionally prescribe...

Lamotrigine - The antiepileptic drug lamotrigine (marketed as Lamictal) is yet another drug that is being used for a different purpose than that for which it was or...

Polymyalgia and seizures - Q My four-year-old daughter started having seizures last April. In just 14 months, she has had a total of eight, one every two weeks. She had just sta...

Druf of the month - Sodium valproate - Sodium valproate also known as valproic acid and marketed under the brand names Epilim, or Depakene or Depakote in the States is a drug used in the tr...

Major seizure link to jabs - The MMR (measles, mumps, rubella) and DTP (diphtheria, tetanus, pertussis) vaccines increase the rate of seizure by more than three times, the most...