Click here to read about some of the people we've helped.  We're here to help you, too. Get four essential health reports by joining our e-news community.

Four FREE health reports for you

Register now for our vital and insightful health updates, and get four free health reports to help you live more healthily.

First Name:Email:


Family matters

Nsaids: - The risks outweigh the benefits for osteoarthritis sufferers

Most osteoarthritis sufferers are still on long-term therapy either with one of the painkilling NSAIDs (non-steroidal, anti-inflammatory drugs) or a COX-2, even though several drugs in both groups have already been banned, and there is growing concern about the rest.
So no doubt assuming the patients' doctors don't read the newspapers or watch television, a research team from the University of Bergen in Norway decided to set about their own study to discover if standard arthritis care is justified - and safe.
They carried out a meta-analysis where they re-analysed the findings from 23 earlier studies, which involved 10,845 patients, of whom 7,807 were taking an NSAID and 3,038 had been given a placebo.
The good news was that the NSAIDs were able to reduce pain in the immediate term - that is, straightaway. By using a pain measurement scale, most patients reported a 15 per cent reduction in paid after taking one of the drugs compared with those who had been given a placebo.
But overall, and over longer periods, the pain reduction decreased significantly and, on average, the NSAID patient was reporting an improvement that was measured as just 0.32 times better than placebo. As researchers might put it, this sort of improvement is 'clinically insignificant', which means that a variable that slight could be affected by many other factors.
But set that marginal benefit against the far likelier chances of a side effect to the NSAID, such as high blood pressure leading to congestive heart failure, and it doesn't take a research physicist to conclude that it isn't worth the risk - which happens to be the conclusion of the Bergen research team.
So what to do instead? Anybody see our story the other week about acupuncture being an effective pain reliever for osteoarthritis sufferers? Just a thought.



WDDTY Blog Speak

Arthritis: nsaid overkill - Paracetamol and simple analgesics are probably just as effective as non steroidal anti inflammatory drugs (NSAIDs) for relieving pain in osteoarthriti...

Nsaids: - How about giving them to cancer patients? - It's truly wonderful the way that drugs companies can reinvent their products, even those that are discredited. The most creative example of this rei...

Nsaids and diuretics causing heart failure - Doctors may be increasing the risk of heart failure among older patients if they are mixing diuretics with NSAIDs (non steroidal anti inflammatory dru...

Nsaids: not to be used for heart disease - It never rains but it pours and, this time, the deluge in the medical press covers the use of non-aspirin non-steroidal anti-inflammatory drugs, or NA...

Nsaid cream: kidney damage - Non steroidal anti inflammatory drugs (NSAIDs) applied to the skin as a cream to reduce pain and swelling may cause potentially lethal kidney damage....

Nsaid use increases risk of miscarriage - NSAIDs (non steroidal anti inflammatory drugs) taken during pregnancy can increase the risk of miscarriage by up to seven times. ...

Drugs that relieve pain: The NSAIDs - Medical studies have demonstrated that a pain-relieving drug – such as an NSAID (non-steroidal, anti-inflammatory drug) or a COX-2 – can help enormous...

Nsaids: fatal ulcer risk - Long term users of NSAIDs (nonsteroidal anti inflammatory drugs) have an increased risk of developing ulcers of the small intestine, which can be life...