In this month's WDDTY - 'Pharmaceutical drugs: in every drop you drink

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Drugs and Side Effects

Eyedrops for glaucoma

My eyes have been diagnosed with narrow-angle, low-pressure chronic glaucoma. Initially, I was prescribed Xalatan (latanoprost) eyedrops once a day. Some time later, I was prescribed brimonidine tartrate eyedrops 0.2 per cent, one drop daily. After a few weeks, the latter caused terrible pain. After some months, I felt very unwell, my eyes were itchy, painful and pink. Eventually, my consultant took me off these drops and I now take AZOPT (brinzolamide) 10 mg/mL twice a day. This gives me no problems.

Nevertheless, my field of vision is deteriorating steadily. Despite pressures down to 10 and 11, an operation has been recommended.

What are the likely side-effects of the eyedrops I am now taking? I have postponed the operation for now, and have started doing yoga for the eyes and cranial osteopathy for my visual nerves. Does anyone know how well this alternative treatment can contain the condition? Under supervision of an alternative therapist, I am also taking various supplements. - IT, Bristol

Latanoprost and brimonidine have become a popular treatment for glaucoma following a study, presented at the American Academy of Ophthalmology in 2001, showing that the combination of eye drugs can lower intraocular pressure more effectively that can other drugs, including the beta-blocker timolol, the former ‘gold-standard’ treatment of glaucoma.

AZOPT (brinzolamide), another family of drug, is the latest glaucoma treatment. Ironically, its most common side-effect is blurred vision and a bitter taste in the mouth. Up to one in 20 users complain of eye infection, ocular discomfort, itching, or watery eyes. Your worsening vision may have something to do with your medication, not just your condition.

Osteopathy can help glaucoma, but be wary of yoga positions that involve inversion.

Some of the best treatments include daily doses of 260-480 mg of bilberry, containing the flavonoid anthocyanidin standardised to 25 per cent (Ann Oph Clin Ocul, 1965; 91: 371-86); 40 mg of Ginkgo (24 per cent ginkgoflavonglycosides) three times a day; and Coleus forskohlii root, an Ayurvedic herb. Emphasise high doses of vitamins A and C, rutin and the B vitamins.

WDDTY Blog Speak

Elective surgery beta-blocker shocker - A recent analysis of 37,151 patients receiving atenolol (a long-acting beta-blocker) or metoprolol (a short-acting beta-blocker) in patients aged over...

Surgical approach to glaucoma treatment - Laser and surgical treatments are available for glaucoma, but these are often aggressive, invasive procedures and, despite advances in technology, sti...

Eyedrops for glaucoma - Other effects - Eyedrops are often considered a benign treatment, and their side-effects on the rest of the body are vastly underappreciated.

Eyedrops for glaucoma - Dangers of eyedrops - Although hailed as a means of delaying the onset of glaucoma, latanoprost (Xalatan) has been shown to cause changes to pigmented tissue. Its continual...

Cellist damaged by vaccine:try cranial osteopathy - Re FL in your case study on meningitis C damage (WDDTY, vol 11 no 6): ...

Look out for preservatives in glaucoma eyedrops - Re ‘Glaucoma’ (WDDTY vol 15 no 12), the preservative in many eyedrops is benzalkonium, which contains a benzene-related chemical that is well document...

Little drops, big problems - Just as we are advised to watch our blood pressure as we get older, the pressure within our eyes is equally at risk with advancing years. Changes in t...

Glaucoma drugs: bronchial link - Beta-blocker eye drops used to treat glaucoma may well cause bronchial problems, including bronchospasms, in elderly patients who never had the sympto...

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